How true is it that COVID-19 vaccine affect fertility?

Even with the misinformation circulating online, there is no evidence that COVID vaccines affect the fertility of women. This misinformation may have first started because an important protein in the development of the placenta (Syncytin-1) has some similarities to the spike protein on the surface of the SARS-CoV-2 virus that causes COVID-19.
“A false claim was made that the antibodies the vaccine would generate might also be directed towards the placenta,” Laura says.

However, since then, there have been many detailed studies comparing the structures of the Syncitin and spike proteins. While some parts of the structures do look the same, they’re no more similar than many other proteins found in our bodies, so it’s highly unlikely that there would be a biological effect. What’s more, there is no evidence so far to show that COVID vaccines can interfere with fertility.

“Even though pregnant women were not planned to be part of the initial vaccine trials, we learned a lot from accidental and unplanned pregnancies that happened within these trials,” Laura says.

Reassuringly, there was no difference in the rate of accidental pregnancies in the group who got the vaccine and those who received a dummy (placebo) jab, strongly suggesting there is no impact on fertility. Researchers are also looking into whether COVID-19 infection itself might affect fertility.

The pandemic has been a challenging time for couples seeking fertility support because many fertility units had to close at certain points or became more limited in the services they have been able to offer. However, for those individuals who were able to access fertility support, there does not seem to have been any effect from the pandemic.

A large study from Italy looked at data from fertility treatment units and found that the outcomes of fertility treatments for couples were just as good after the pandemic started, as before. Some people may also wonder about vaccines and male fertility. This has been studied and there is no evidence that sperm counts, motility or fertility are affected by vaccination.

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